What is Sinomarin
 How does Sinomarin work?
 Nasal irrigation & decongestion
 Indications for using Sinomarin
 When should Sinomarin be used


Nasal irrigation & decongestion

The use of nasal irrigation dates back centuries to yogic and ayurvedic traditions where hypertonic saline solutions were used for nasal irrigation for purification purposes as part of the preparation process. Western medicine has adopted this practice since the 19th century where nasal irrigation has been recommended for the treatment of sinonasal pathology.

Nasal irrigation and thus cleansing -performed using a neti pot (neti in Sanskrit means "nasal cleansing"), nebulizers or most commonly nasal sprays- is being used extensively in modern medicine to flush out dust, debris, pollutants, allergens, germs and excess mucus from the nose and sinuses which can lead to sinonasal blockage and infection.

Whereas nasal irrigation can be carried out using ordinary tap water, this is generally felt to be uncomfortable because it irritates the mucous membranes. Therefore an isotonic or hypertonic salt water solution is normally used.

Hypertonic vs. Isotonic

Salt water solutions are generally divided into isotonic -where the concentration of salt is equal to the natural concentration in our bodies (0.9%)- and hypertonic -where the salt concentration is higher than what would normally be in our bodies (>0.9%). Moreover, salt water solutions are further divided into saline solutions (purified water plus sodium chloride) and seawater (containing sodium chloride, minerals and trace elements).

Whereas isotonic solutions are suitable for nasal cleansing, they cannot function as decongestants. This is because they have the same salt concentration with the sinonasal tissues. However, hypertonic solutions, in addition to nasal cleansing, can be considered as natural decongestants as they have a higher salt concentration than the tissues. In this way, hypertonic solutions are able to “draw out” excess water from the mucous membranes (though the process of osmosis), thus reduce the space the inflamed tissues occupy in the nasal cavities in addition to diluting the viscous mucous that has accumulated. Moreover, it has been demonstrated scientifically that, the tiny hair-like projections called cilia (see know your nose section) which are responsible for moving mucous and dirt particles away from the nose and are found to dysfunction under certain conditions, improve with hypertonic solutions. However, too high a concentration of salt ~>3% has been shown to opposite effects on cilia function in addition to being irritable for the sinonasal mucosa. Gargling with saltwater can also relieve a sore throat.

Seawater is enriched with trace elements. Trace elements are essential for life. It is thus considered that saltwater solutions are more beneficial than simple saline solutions.

Hypertonic seawater thus, differs from isotonic water in that it:
• Decongests the mucosa through nasal drainage
• Improves the function of mucosal cilia and therefore the removal of dirt and mucous

As a result, hypertonic seawater has shown clinically to:
• Decrease the consumption of medication such as anti-histamines
• Improve quality of life
• Is suitable for the use by pregnant women